I sincerely look for the help of you guys. This is actually a bit personal but it would also benefit many to open a dedicated thread for this issue. I'm sure most of you are familiar with it.
For my story, click here: https://www.hairlosstalk.com/intera...ime-and-androgen-receptor-upregulation.99512/
First of all we all know that itch and inflammation are typical symptoms of male pattern baldness. Androgens (mainly DHT) activate androgen receptors causing a series of reactions (in which PGD2 is thought to play a role) resulting in your immune system attacking your own hair follicles. At least that's what I gathered from reading and discussion so far.
I'm suffering from severe itch and inflammation now. While it's true that I was never free of itch back in all those years on finasteride, I do think it alleviated them to some extent. My itch/inflammation happens where I lose hair, which is the whole crown area, hairline, two large areas above my temples, and the hairline on the back of my head (yes you read it right the hairline on the back). All these areas have thinner hair except for the hairline on the back. I was never freed from shedding either, but I'd shed 30+ hairs per day. Considering the amount of hair I had it was fairly acceptable.
For a good 7 years I was able to keep the remaining hair. The itch was never unmanagable if I use the right shampoo. But ever since I found what finasteride was actually doing to my body and started microdosing (starting from May 2016), my itch and inflammation has gone so wild they're completely out of control! Back then I used to wash my hair every three days and the sebum & itch only got annoying on the third day. Now I can be washing my head everyday and still suffer from this itch right after washing. It's literally making it hard for me to concentrate on my life. (I guess @Dench57 has something to say about that too?) I have no flakes or scales, so I don't think it's the fungus. Just itch and inflammation like hell. They leave red dots and pimples on my head.
I don't think this happened overnight. In the summer back in 2015 I already noticed increased itch and shedding, but back then I got a lot of heat and sunburn in Italy and the itch subsided after 1 month so I didn't think too much. The itch and shedding I'm experiencing now is exactly in the same pattern except much worse. It has lasted for two months and keeps deteriorating.
So, what's happening to my scalp on earth??
Is it because I lowered my finasteride dosage?
Maybe, but I paused finasteride for multiple times in the past years, with the longest period of a good 3 months. Even though back then I noticed slightly thinning crown, I don't remember getting this insane itch! Also note that finasteride never fully got rid of the itch before.Is it because of hyperandrogenecity or androgen receptor upregulation? I do think it's very likely, but while my scalp keeps getting fxxked up, the other areas on my face and body show no sign of this. Facial/body sebum production is the same. I'm not getting additional acnes or rashes either. This is not the case described by dench and makes no sense since oral finasteride works globally. Also note that my sex drive never bounces back (actually I think it is getting lower).
Is it because of the summer heat and seasonal shedding? I really don't think so since I've never experienced anything to this extent in the past years. But I'm sure the summer is making it worse.
Finally, what would you suggest to fight this itch?
Are we simply doomed without finasteride stopping the male pattern baldness itch?
Nizoral won't help at all. A long list of natural supplements won't help. RU relieves the itch almost instantly but the sides are immediate too. @David_MPN recommended Paul Mitchel's tea tree oil shampoo (thanks for that mate!), which I haven't tried and probably can't because they don't retail in my area. I'm looking into CB and Seti right now but I'm just so distracted and worried since I was so fxxked up by anti androgens and seti seems to cause sleep problems.Sometimes I think I'd just let hair go and shave my head some day but even then I can't live my life with this terrible itch...
Advices are appreciated and discussions are welcomed! Please, I need your help.